The AXP™ AutoXpress™ Platform is
an automated, fully closed, sterile system that volume reduces
cord blood to a precise 20 ml in less than 40 min, while retaining
> 97% mononucleated cells (MNCs)*. The AXP™ Platform
comprises the AXP device, docking station, processing set,
and XpressTRAK™ software that assists with cGMP and
cGTP compliance.
The AXP™ device is self-powered and microprocessor-controlled.
It contains flow control optical sensors that are used to
achieve the separation of a concentrated MNC fraction of uniform
volume (nominally 20 ml). The device is powered by a NiMH
battery that is recharged concurrent with data downloading
in a docking station.
Cord blood, transferred to the processing set, is placed
in the device and centrifuged. A mononuclear cell (MNC) fraction
is established, separated and automatically delivered to a
blow-molded freezing bag designed for optimal spacesaving
storage. Excess red blood cells (RBC) and plasma are delivered
to connected sterile bags. The AXP™ device fits into
most standard refrigerated blood bank centrifuge buckets and
can process six units at one time. MNC separation in the AXP™
system does not require hetastarch.
The AXP™ Platform is designed to capture essential
data for quality assurance and compliance with current good
tissue practices (cGTP). XpressTRAK™ software tracks
and documents each cord blood unit’s separation data
during and after centrifugation. Other data fields (blood
unit ID, user ID, centrifuge ID, and processing bag lot number/expiration
date) are entered via a keyboard or a wireless scanner. The
software produces a printable report of the processing cycle
and stores the data in a searchable, sortable database. Additional
features of the software include the ability to modify an
ISBT 128 barcode to identify a split-bag sample, run QC testing
on AXP devices, assist with troubleshooting, and prepare reports
on device history.
AXP
& BioArchive Total Solution Video (modem 575k)
AXP & BioArchive
Total Solution Video (broadband 5MB)
For more information on the AXP™ AutoXpress™
Platform, contact ThermoGenesis
Corp. or GE Healthcare
* Data provided by New York Blood Center (97.9% sd 4.9%). |
